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Robust Electrospinning-Constructed Cellulose Acetate@Anthocyanin Ultrafine Fibers: Synthesis, Characterization, and Controlled Release Properties

Anthocyanin has attracted increasing attention due to its superior biological activity. However, the inherently poor stability of anthocyanin limits its practical applications. In this study, a fast and straightforward method was developed to improve the stability of anthocyanin. Cellulose acetate ultrafine fiber-loaded anthocyanin (CA@Anthocyanin UFs) was prepared by robust electrospinning, and the potential application of cellulose acetate ultrafine fibers (CA UFs) as a bioactive substance delivery system was comprehensively investigated. The experimental results showed that CA@Anthocyanin UFs had protective effects on anthocyanin against temperature, light, and pH. The results of the artificially simulated gastric fluid (pH = 2.0) indicated that the CA@Anthocyanin UFs had a controllable release influence on anthocyanin. A 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay suggested that the CA@Anthocyanin UFs still had an excellent antioxidant activity similar to anthocyanin. This work demonstrated the potential application of robust electrospinning-constructed cellulose acetate ultrafine fibers in bioactive substance delivery and controlled release systems, as well as its prospects in green packaging due to the nature of this environmentally friendly composite.

Publication date: 27/09/2022

Author: Mingzhu Liu

Reference: doi: 10.3390/polym14194036

MDPI (polymers)


This project has received funding from the Bio Based Industries Joint Undertaking under the European Union’s Horizon 2020 research and innovation programme under grant agreement No 837761.